About 1 result found for searched term "PF-04577806 " (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27750 | PF-04577806 | PKC |
| PF-04577806 is a potent, selective and ATP competitive PKC inhibitor. PF-04577806 shows potent inhibitory activity towards PKCα, PKCβI, PKCβII, PKCγ, and PKCθ with IC50s of 2.4 nM, 8.1 nM, 6.9 nM, 45.9 nM, and 29.5 nM, respectively. PF-04577806 can reverse retinal vascular leakage in diabetic rats. | ||
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